Reviews

Brief review: Cardiac complications and platelet activation in COVID-19 infection

C Feldman, R Anderson

Abstract


COVID-19 pneumonia, much like that of bacterial and viral community-acquired pneumonia before it, is accompanied by a high rate of cardio- and cerebrovascular events that are associated with an increased risk of complications and a greater mortality. Although the mechanisms underlying the pathogenesis of these adverse events are not entirely clear and may be multifactorial, platelets appear to have a prominent aetiologic role and this, together with an overview of the clinical evidence, forms the basis of this short review.

Authors' affiliations

C Feldman, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

R Anderson, Department of Immunology, Faculty of Health Sciences, University of Pretoria, South Africa

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Cite this article

African Journal of Thoracic and Critical Care Medicine 2020;26(3):90-94. DOI:10.7196/AJTCCM.2020.v26i3.107

Article History

Date submitted: 2020-09-16
Date published: 2020-10-13

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African Journal of Thoracic and Critical Care Medicine| Online ISSN: 2617-0205

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